There’s no such thing as a lock in sports betting.

A BetMGM bettor in Nevada learned that the hard way Thursday night, losing a $25,000 wager on Carlos Alcaraz to win his second-round match at the U.S. Open as a -10,000 favorite. The bet would’ve paid $250 had Alcaraz won.

Alcaraz, bidding to win his third straight Grand Slam, and the bettor were shocked when the world’s No. 3-ranked player lost in straight sets — 6-1, 7-5, 6-4 — to Botic van de Zandschulp, ranked 74th in the world.

Alcaraz, a Spaniard, defeated van de Zandshulp of the Netherlands in straight sets in their previous two matches.

Contact reporter Todd Dewey at [email protected]. Follow @tdewey33 on X.